There is a new kind of buzz in the anesthesia community these days. News of a “selective” muscle relaxant binding agent hit the web in a big way. Even Forbes made notice. Sugammadex, a proprietary cyclodextrin available from Organon, has the ability to bring post-operative patients out from under the influence of muscle relaxant drugs rapidly and safely. It does this by host-guest coordination of drug molecules in the blood stream, effectively lowering the blood titer of active drug. The cyclodextrin acts as a kind of sheath or molecular condom to prevent binding of the certain active relaxant drugs to the receptors. The results are apparently startling to the numbing and gas passing community. 

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