Disposable reactors are here. According to ICIS, Marlborough, MA, based Xcellerex is offering disposable bioreactors for biologics manufacture.  These single-use reactors are available in the 40-2000 Liter working volume range.  The company offers several reasons for why their product might be desirable. They argue that more time will be available for productive reactor operation as opposed to having production down part of the time for reactor cleanout and validation.

The battle for high throughput moves to a new level. Xcellerex states that the installed capital cost is ca 1/2 that of hardpiped reactors. They make the case that delays due to cleaning are reduced and that plant time is used more efficiently.